Endocrine Abstracts

Lipocalin 2 has become an important biomarker for kidney disease and it is important to now understand it’s role in cardiomyopathy and understand it’s direct effects on the heart. Autophagy is now established as a critical determinant of cardiac function and here we investigated regulation of cardiac autophagy by lipocalin-2 and the functional consequences. After treating H9c2 cells with lipocalin-2 we used transmission electron microscopy, Western blotting and immun...